.chemrytiq-page .chemrytiq-result-tab[data-chemrytiq-result-tab="denovo"]::before {
  content: "DN";
}

.chemrytiq-page .chemrytiq-denovo-workspace {
  color: var(--chemrytiq-text, #12304d);
  font-family: inherit;
  font-size: 0.92rem;
  line-height: 1.45;
}

.chemrytiq-page .chemrytiq-denovo-workspace * {
  font-family: inherit;
}

.chemrytiq-page .chemrytiq-denovo-shell {
  display: grid;
  gap: 1rem;
}

.chemrytiq-page .chemrytiq-denovo-header,
.chemrytiq-page .chemrytiq-denovo-card {
  border: 1px solid var(--chemrytiq-border, rgba(80, 102, 142, 0.18));
  border-radius: var(--chemrytiq-radius-md, 1rem);
  background: var(--chemrytiq-surface, #ffffff);
  box-shadow: none;
}

.chemrytiq-page .chemrytiq-denovo-header {
  display: flex;
  align-items: flex-start;
  justify-content: space-between;
  gap: 1rem;
  padding: 1.1rem 1.2rem;
}

.chemrytiq-page .chemrytiq-denovo-kicker,
.chemrytiq-page .chemrytiq-denovo-section-label {
  display: block;
  color: #315f8f;
  font-size: 0.76rem;
  font-weight: 900;
  letter-spacing: 0;
  text-transform: uppercase;
}

.chemrytiq-page .chemrytiq-denovo-section-label--with-action {
  display: flex;
  align-items: center;
  flex-wrap: wrap;
  gap: 0.65rem;
}

.chemrytiq-page .chemrytiq-denovo-inline-generate {
  min-height: 1.9rem;
  padding: 0 0.7rem;
  text-transform: none;
}

.chemrytiq-page .chemrytiq-denovo-inline-clear-analogs {
  min-height: 1.9rem;
  padding: 0 0.7rem;
  border: 1px solid #c5d7eb;
  border-radius: 999px;
  background: #ffffff;
  color: #315f8f;
  font-weight: 800;
  text-transform: none;
  cursor: pointer;
}

.chemrytiq-page .chemrytiq-denovo-inline-generate:not(:disabled) {
  border-color: #1976d2;
  background: #1976d2;
  color: #ffffff;
  box-shadow: 0 8px 18px rgba(25, 118, 210, 0.18);
}

.chemrytiq-page .chemrytiq-denovo-inline-clear-analogs:not(:disabled):hover {
  border-color: #1976d2;
  color: #0f5599;
  box-shadow: 0 8px 18px rgba(49, 95, 143, 0.12);
}

.chemrytiq-page .chemrytiq-denovo-inline-clear-analogs:disabled {
  opacity: 0.55;
  cursor: not-allowed;
}

.chemrytiq-page .chemrytiq-denovo-header h2,
.chemrytiq-page .chemrytiq-denovo-card h3 {
  margin: 0.15rem 0 0;
  color: var(--chemrytiq-text, #12304d);
  letter-spacing: 0;
}

.chemrytiq-page .chemrytiq-denovo-header h2 {
  font-size: 1.18rem;
  font-weight: 800;
  line-height: 1.25;
}

.chemrytiq-page .chemrytiq-denovo-card h3 {
  font-size: 1rem;
  font-weight: 800;
  line-height: 1.25;
}

.chemrytiq-page .chemrytiq-denovo-header p {
  max-width: 58rem;
  margin: 0.4rem 0 0;
  color: var(--chemrytiq-text-soft, #445d73);
  font-size: 0.9rem;
  line-height: 1.5;
}

.chemrytiq-page .chemrytiq-denovo-grid {
  display: grid;
  grid-template-columns: minmax(18rem, 1.1fr) minmax(15rem, 0.9fr) minmax(15rem, 0.9fr);
  gap: 1rem;
}

.chemrytiq-page .chemrytiq-denovo-card {
  padding: 1rem;
}

.chemrytiq-page .chemrytiq-denovo-card-head {
  display: flex;
  align-items: flex-start;
  justify-content: space-between;
  gap: 1rem;
  margin-bottom: 0.85rem;
}

.chemrytiq-page .chemrytiq-denovo-field {
  display: grid;
  gap: 0.4rem;
  color: var(--chemrytiq-text-soft, #445d73);
  font-size: 0.88rem;
  font-weight: 800;
}

.chemrytiq-page .chemrytiq-denovo-field textarea {
  width: 100%;
  min-height: 7rem;
  resize: vertical;
  border: 1px solid var(--chemrytiq-border-strong, #c5d4e5);
  border-radius: var(--chemrytiq-radius-sm, 0.75rem);
  background: #ffffff;
  padding: 0.75rem;
  color: var(--chemrytiq-text, #12304d);
  font: 0.9rem/1.45 ui-monospace, SFMono-Regular, Consolas, "Liberation Mono", monospace;
}

.chemrytiq-page .chemrytiq-denovo-field textarea:focus {
  border-color: #1976d2;
  box-shadow: 0 0 0 3px rgba(25, 118, 210, 0.12);
  outline: none;
}

.chemrytiq-page .chemrytiq-denovo-actions {
  display: flex;
  flex-wrap: wrap;
  gap: 0.55rem;
  margin-top: 0.7rem;
}

.chemrytiq-page .chemrytiq-denovo-primary,
.chemrytiq-page .chemrytiq-denovo-secondary,
.chemrytiq-page .chemrytiq-denovo-actions button {
  display: inline-flex;
  align-items: center;
  justify-content: center;
  min-height: 2.35rem;
  border: 1px solid #1976d2;
  border-radius: 999px;
  background: #1976d2;
  color: #ffffff;
  cursor: pointer;
  font-size: 0.84rem;
  font-weight: 800;
  line-height: 1;
  padding: 0 0.85rem;
}

.chemrytiq-page .chemrytiq-denovo-secondary,
.chemrytiq-page .chemrytiq-denovo-actions button + button {
  border-color: var(--chemrytiq-border-strong, #c5d4e5);
  background: #ffffff;
  color: #1565c0;
}

.chemrytiq-page .chemrytiq-denovo-primary:hover,
.chemrytiq-page .chemrytiq-denovo-actions button:first-child:hover {
  background: #1565c0;
  border-color: #1565c0;
}

.chemrytiq-page .chemrytiq-denovo-secondary:hover,
.chemrytiq-page .chemrytiq-denovo-actions button + button:hover {
  background: #eef5ff;
  border-color: #bdd3f0;
}

.chemrytiq-page .chemrytiq-denovo-primary:disabled,
.chemrytiq-page .chemrytiq-denovo-secondary:disabled,
.chemrytiq-page .chemrytiq-denovo-actions button:disabled {
  cursor: not-allowed;
  opacity: 0.58;
}

.chemrytiq-page .chemrytiq-denovo-note {
  display: grid;
  gap: 0.25rem;
  margin-top: 0.8rem;
  border: 1px solid rgba(17, 100, 61, 0.16);
  border-left: 4px solid #2e7d32;
  border-radius: var(--chemrytiq-radius-sm, 0.75rem);
  background: #f3fbf5;
  padding: 0.7rem 0.8rem;
  color: #315b3a;
  font-size: 0.86rem;
  line-height: 1.45;
}

.chemrytiq-page .chemrytiq-denovo-status,
.chemrytiq-page .chemrytiq-denovo-pill {
  border-radius: 999px;
  background: #e8f0fa;
  color: #315f8f;
  font-size: 0.76rem;
  font-weight: 800;
  padding: 0.32rem 0.58rem;
  white-space: nowrap;
}

.chemrytiq-page .chemrytiq-denovo-status[data-tone="good"],
.chemrytiq-page .chemrytiq-denovo-pill[data-tone="good"] {
  background: #e8f5e9;
  color: #1b6b31;
}

.chemrytiq-page .chemrytiq-denovo-status[data-tone="watch"],
.chemrytiq-page .chemrytiq-denovo-pill[data-tone="watch"] {
  background: #fff7e5;
  color: #946200;
}

.chemrytiq-page .chemrytiq-denovo-status[data-tone="working"] {
  background: #e8f1ff;
  color: #0f5f9f;
}

.chemrytiq-page .chemrytiq-denovo-pill[data-tone="risk"] {
  background: #fdecec;
  color: #a33131;
}

.chemrytiq-page .chemrytiq-denovo-structure {
  display: grid;
  min-height: 15rem;
  place-items: center;
  border: 1px solid var(--chemrytiq-border, #d7e3ef);
  border-radius: var(--chemrytiq-radius-sm, 0.75rem);
  background: var(--chemrytiq-surface-soft, #f7fbff);
  color: var(--chemrytiq-text-soft, #445d73);
  overflow: hidden;
  padding: 0.7rem;
}

.chemrytiq-page .chemrytiq-denovo-structure svg {
  width: 100%;
  max-height: 14rem;
}

.chemrytiq-page .chemrytiq-denovo-structure code {
  max-width: 100%;
  white-space: normal;
  word-break: break-all;
}

.chemrytiq-page .chemrytiq-denovo-objectives {
  display: grid;
  gap: 0.45rem;
}

.chemrytiq-page .chemrytiq-denovo-objectives label {
  display: flex;
  align-items: center;
  gap: 0.5rem;
  min-height: 2.15rem;
  border: 1px solid var(--chemrytiq-border, #d7e3ef);
  border-radius: 999px;
  background: var(--chemrytiq-surface-soft, #f7fbff);
  color: var(--chemrytiq-text-soft, #445d73);
  cursor: pointer;
  font-size: 0.84rem;
  font-weight: 800;
  padding: 0.45rem 0.6rem;
}

.chemrytiq-page .chemrytiq-denovo-objectives label:has(input:checked) {
  border-color: rgba(25, 118, 210, 0.36);
  background: #eef6ff;
  color: #174d7d;
}

.chemrytiq-page .chemrytiq-denovo-objectives input {
  accent-color: #1976d2;
}

.chemrytiq-page .chemrytiq-denovo-property-grid {
  display: grid;
  grid-template-columns: repeat(10, minmax(0, 1fr));
  gap: 0.5rem;
}

.chemrytiq-page .chemrytiq-denovo-property {
  display: grid;
  gap: 0.25rem;
  min-height: 3.55rem;
  border: 1px solid rgba(80, 102, 142, 0.16);
  border-radius: var(--chemrytiq-radius-sm, 0.75rem);
  background: #f9fbfd;
  padding: 0.55rem 0.6rem;
}

.chemrytiq-page .chemrytiq-denovo-property span {
  color: #69778c;
  font-size: 0.68rem;
  font-weight: 800;
  text-transform: uppercase;
}

.chemrytiq-page .chemrytiq-denovo-property strong {
  min-width: 0;
  color: #172033;
  font-size: 0.88rem;
  overflow-wrap: anywhere;
}

.chemrytiq-page .chemrytiq-denovo-empty {
  grid-column: 1 / -1;
  border: 1px solid var(--chemrytiq-border, #d7e3ef);
  border-radius: var(--chemrytiq-radius-sm, 0.75rem);
  background: var(--chemrytiq-surface-soft, #f7fbff);
  color: var(--chemrytiq-text-soft, #445d73);
  padding: 0.9rem;
}

.chemrytiq-page .chemrytiq-denovo-table-wrap {
  overflow-x: auto;
}

.chemrytiq-page .chemrytiq-denovo-ranking {
  display: flex;
  flex-wrap: wrap;
  gap: 0.8rem;
  align-items: stretch;
  margin-bottom: 0.8rem;
}

.chemrytiq-page .chemrytiq-denovo-ranking[hidden],
.chemrytiq-page .chemrytiq-denovo-sar-map[hidden],
.chemrytiq-page .chemrytiq-denovo-detail[hidden] {
  display: none;
}

.chemrytiq-page .chemrytiq-denovo-top-candidate {
  display: grid;
  gap: 0.18rem;
  flex: 0 1 34rem;
  border: 1px solid rgba(17, 100, 61, 0.2);
  border-radius: var(--chemrytiq-radius-sm, 0.75rem);
  background: #f4fbf6;
  padding: 0.65rem 0.75rem;
}

.chemrytiq-page .chemrytiq-denovo-top-candidate span,
.chemrytiq-page .chemrytiq-denovo-sort span {
  color: #69778c;
  font-size: 0.7rem;
  font-weight: 900;
  text-transform: uppercase;
}

.chemrytiq-page .chemrytiq-denovo-top-candidate strong {
  color: #172033;
  font-size: 0.95rem;
}

.chemrytiq-page .chemrytiq-denovo-top-candidate em {
  color: var(--chemrytiq-text-soft, #445d73);
  font-size: 0.82rem;
  font-style: normal;
}

.chemrytiq-page .chemrytiq-denovo-sort {
  display: grid;
  gap: 0.25rem;
  flex: 0 1 16rem;
  align-self: stretch;
}

.chemrytiq-page .chemrytiq-denovo-sort select {
  min-height: 2.2rem;
  border: 1px solid var(--chemrytiq-border-strong, #c5d4e5);
  border-radius: 999px;
  background: #ffffff;
  color: var(--chemrytiq-text, #12304d);
  font-size: 0.84rem;
  font-weight: 800;
  padding: 0 0.75rem;
}

.chemrytiq-page .chemrytiq-denovo-collapse {
  border: 1px solid var(--chemrytiq-border, #d7e3ef);
  border-radius: var(--chemrytiq-radius-sm, 0.75rem);
  background: #ffffff;
}

.chemrytiq-page .chemrytiq-denovo-collapse summary {
  cursor: pointer;
  color: #315f8f;
  font-size: 0.78rem;
  font-weight: 900;
  list-style-position: inside;
  padding: 0.6rem 0.7rem;
  text-transform: uppercase;
}

.chemrytiq-page .chemrytiq-denovo-collapse[open] summary {
  border-bottom: 1px solid var(--chemrytiq-border, #d7e3ef);
  background: #f8fbff;
}

.chemrytiq-page .chemrytiq-denovo-sort-collapse {
  flex: 0 1 18rem;
  align-self: stretch;
}

.chemrytiq-page .chemrytiq-denovo-sort-collapse .chemrytiq-denovo-sort {
  padding: 0.7rem;
}

.chemrytiq-page .chemrytiq-denovo-sar-map {
  border: 1px solid var(--chemrytiq-border, #d7e3ef);
  border-radius: var(--chemrytiq-radius-sm, 0.75rem);
  background: #ffffff;
  margin: 0 0 0.9rem;
  overflow: hidden;
}

.chemrytiq-page .chemrytiq-denovo-sar-head {
  border-bottom: 1px solid var(--chemrytiq-border, #d7e3ef);
  background: #f8fbff;
  display: flex;
  align-items: center;
  justify-content: space-between;
  gap: 0.8rem;
  padding: 0.7rem 0.8rem;
}

.chemrytiq-page .chemrytiq-denovo-sar-head div {
  display: grid;
  gap: 0.14rem;
}

.chemrytiq-page .chemrytiq-denovo-sar-head span,
.chemrytiq-page .chemrytiq-denovo-sar-head small {
  color: #69778c;
  font-size: 0.7rem;
  font-weight: 900;
  line-height: 1.2;
  text-transform: uppercase;
}

.chemrytiq-page .chemrytiq-denovo-sar-head strong {
  color: #172033;
  font-size: 0.95rem;
  line-height: 1.2;
}

.chemrytiq-page .chemrytiq-denovo-sar-body {
  display: grid;
  grid-template-columns: minmax(18rem, 0.85fr) minmax(18rem, 1.15fr);
  gap: 0.85rem;
  padding: 0.85rem;
}

.chemrytiq-page .chemrytiq-denovo-sar-structure {
  position: relative;
  min-height: 17rem;
  border: 1px solid rgba(80, 102, 142, 0.13);
  border-radius: 8px;
  background: #fbfdff;
  display: grid;
  place-items: center;
  overflow: hidden;
}

.chemrytiq-page .chemrytiq-denovo-sar-structure svg {
  width: 100%;
  max-width: 25rem;
  height: auto;
}

.chemrytiq-page .chemrytiq-denovo-sar-overlay {
  position: absolute;
  inset: 0;
  pointer-events: none;
}

.chemrytiq-page .chemrytiq-denovo-sar-overlay button {
  position: absolute;
  width: 2.15rem;
  height: 2.15rem;
  transform: translate(-50%, -50%) scale(var(--sar-scale, 1));
  border: 2px solid rgba(255, 255, 255, 0.92);
  border-radius: 999px;
  background: #d92d20;
  box-shadow: 0 0 0 0.28rem rgba(217, 45, 32, 0.16), 0 0.55rem 1.4rem rgba(23, 32, 51, 0.18);
  color: #ffffff;
  cursor: pointer;
  font-size: 0.82rem;
  font-weight: 900;
  pointer-events: auto;
}

.chemrytiq-page .chemrytiq-denovo-sar-list {
  display: grid;
  gap: 0.45rem;
}

.chemrytiq-page .chemrytiq-denovo-sar-list button {
  border: 1px solid rgba(80, 102, 142, 0.16);
  border-left: 4px solid #d92d20;
  border-radius: 8px;
  background: #ffffff;
  cursor: pointer;
  display: grid;
  gap: 0.18rem;
  padding: 0.55rem 0.65rem;
  text-align: left;
}

.chemrytiq-page .chemrytiq-denovo-sar-list button:hover,
.chemrytiq-page .chemrytiq-denovo-sar-list button:focus {
  border-color: rgba(25, 118, 210, 0.34);
  box-shadow: 0 0 0 3px rgba(25, 118, 210, 0.1);
  outline: none;
}

.chemrytiq-page .chemrytiq-denovo-sar-list b {
  color: #172033;
  font-size: 0.84rem;
  line-height: 1.2;
}

.chemrytiq-page .chemrytiq-denovo-sar-list span,
.chemrytiq-page .chemrytiq-denovo-sar-list small,
.chemrytiq-page .chemrytiq-denovo-sar-list em {
  color: #526176;
  font-size: 0.74rem;
  font-style: normal;
  font-weight: 750;
  line-height: 1.25;
}

.chemrytiq-page .chemrytiq-denovo-sar-list small {
  color: #172033;
  font-weight: 850;
}

.chemrytiq-page .chemrytiq-denovo-table {
  width: 100%;
  min-width: 82rem;
  border-collapse: collapse;
  border: 1px solid var(--chemrytiq-border, #d7e3ef);
  border-radius: var(--chemrytiq-radius-sm, 0.75rem);
  overflow: hidden;
  table-layout: fixed;
}

.chemrytiq-page .chemrytiq-denovo-table th:nth-child(1),
.chemrytiq-page .chemrytiq-denovo-table td:nth-child(1) {
  width: 9rem;
}

.chemrytiq-page .chemrytiq-denovo-table th:nth-child(2),
.chemrytiq-page .chemrytiq-denovo-table td:nth-child(2) {
  width: 25%;
}

.chemrytiq-page .chemrytiq-denovo-table th:nth-child(3),
.chemrytiq-page .chemrytiq-denovo-table td:nth-child(3) {
  width: 24%;
}

.chemrytiq-page .chemrytiq-denovo-table th:nth-child(4),
.chemrytiq-page .chemrytiq-denovo-table td:nth-child(4) {
  width: 25%;
}

.chemrytiq-page .chemrytiq-denovo-table th:nth-child(5),
.chemrytiq-page .chemrytiq-denovo-table td:nth-child(5) {
  width: 14rem;
}

.chemrytiq-page .chemrytiq-denovo-table th:nth-child(6),
.chemrytiq-page .chemrytiq-denovo-table td:nth-child(6) {
  width: 9.4rem;
}

.chemrytiq-page .chemrytiq-denovo-table th:nth-child(7),
.chemrytiq-page .chemrytiq-denovo-table td:nth-child(7) {
  width: 6.5rem;
}

.chemrytiq-page .chemrytiq-denovo-table th,
.chemrytiq-page .chemrytiq-denovo-table td {
  border-bottom: 1px solid var(--chemrytiq-border, #d7e3ef);
  padding: 0.7rem;
  text-align: left;
  vertical-align: top;
}

.chemrytiq-page .chemrytiq-denovo-table tbody tr {
  cursor: pointer;
}

.chemrytiq-page .chemrytiq-denovo-table tbody tr.is-selected {
  background: #f8fbff;
  box-shadow: inset 4px 0 0 #1976d2;
}

.chemrytiq-page .chemrytiq-denovo-more-row,
.chemrytiq-page .chemrytiq-denovo-more-row:hover {
  cursor: default;
  background: #ffffff;
  box-shadow: none;
}

.chemrytiq-page .chemrytiq-denovo-more-row > td {
  padding: 0.65rem;
}

.chemrytiq-page .chemrytiq-denovo-more-analogs {
  background: #ffffff;
}

.chemrytiq-page .chemrytiq-denovo-table--nested {
  min-width: 68rem;
  border: 0;
  border-radius: 0;
  margin: 0;
}

.chemrytiq-page .chemrytiq-denovo-table--nested tr:last-child td {
  border-bottom: 0;
}

.chemrytiq-page .chemrytiq-denovo-table th {
  background: #f8fbff;
  color: var(--chemrytiq-text-soft, #445d73);
  font-size: 0.75rem;
  text-transform: uppercase;
}

.chemrytiq-page .chemrytiq-denovo-table td {
  color: var(--chemrytiq-text-soft, #445d73);
}

.chemrytiq-page .chemrytiq-denovo-table td code {
  display: block;
  width: 100%;
  max-width: 100%;
  box-sizing: border-box;
  border-radius: 0.45rem;
  background: #f8fbff;
  color: #172033;
  font-size: 0.78rem;
  line-height: 1.35;
  overflow: hidden;
  overflow-wrap: break-word;
  white-space: normal;
  word-break: break-all;
  padding: 0.35rem 0.45rem;
}

.chemrytiq-page .chemrytiq-denovo-analog-cell > strong {
  display: inline-flex;
  width: fit-content;
  border-radius: 999px;
  background: #e8f0fa;
  color: #315f8f;
  font-size: 0.72rem;
  font-weight: 900;
  margin-bottom: 0.35rem;
  padding: 0.16rem 0.45rem;
}

.chemrytiq-page .chemrytiq-denovo-table td strong,
.chemrytiq-page .chemrytiq-denovo-table td span,
.chemrytiq-page .chemrytiq-denovo-table td em,
.chemrytiq-page .chemrytiq-denovo-table td small {
  display: block;
}

.chemrytiq-page .chemrytiq-denovo-table td strong {
  color: #172033;
  font-size: 0.88rem;
  line-height: 1.3;
}

.chemrytiq-page .chemrytiq-denovo-table td em,
.chemrytiq-page .chemrytiq-denovo-table td small {
  color: var(--chemrytiq-text-soft, #445d73);
  font-size: 0.76rem;
  font-style: normal;
  line-height: 1.35;
  margin-top: 0.25rem;
}

.chemrytiq-page .chemrytiq-denovo-mini-structure {
  display: grid;
  width: 8rem;
  min-height: 5.5rem;
  place-items: center;
  border: 1px solid var(--chemrytiq-border, #d7e3ef);
  border-radius: var(--chemrytiq-radius-sm, 0.75rem);
  background: var(--chemrytiq-surface-soft, #f7fbff);
  overflow: hidden;
  padding: 0.35rem;
}

.chemrytiq-page .chemrytiq-denovo-mini-structure svg {
  width: 100%;
  max-height: 5rem;
}

.chemrytiq-page .chemrytiq-denovo-mini-structure span {
  color: #315f8f;
  font-size: 0.8rem;
  font-weight: 900;
}

.chemrytiq-page .chemrytiq-denovo-deltas {
  display: flex;
  flex-wrap: wrap;
  gap: 0.3rem;
  margin-top: 0.35rem;
}

.chemrytiq-page .chemrytiq-denovo-deltas span {
  border: 1px solid rgba(80, 102, 142, 0.14);
  border-radius: 999px;
  background: #ffffff;
  color: #526176;
  font-size: 0.72rem;
  font-weight: 800;
  padding: 0.18rem 0.42rem;
}

.chemrytiq-page .chemrytiq-denovo-score {
  display: grid;
  min-width: 0;
  gap: 0.1rem;
  border: 1px solid rgba(80, 102, 142, 0.16);
  border-radius: var(--chemrytiq-radius-sm, 0.75rem);
  background: #f9fbfd;
  padding: 0.42rem 0.5rem;
}

.chemrytiq-page .chemrytiq-denovo-score b {
  color: #172033;
  font-size: 1rem;
  line-height: 1;
}

.chemrytiq-page .chemrytiq-denovo-score small {
  color: #69778c;
  font-size: 0.68rem;
  font-weight: 800;
  line-height: 1.2;
  margin: 0;
  text-transform: uppercase;
}

.chemrytiq-page .chemrytiq-denovo-score-grid {
  display: grid;
  grid-template-columns: repeat(2, minmax(0, 1fr));
  gap: 0.4rem;
}

.chemrytiq-page .chemrytiq-denovo-score[data-tone="good"] {
  border-color: rgba(17, 100, 61, 0.24);
  background: #f4fbf6;
}

.chemrytiq-page .chemrytiq-denovo-score[data-tone="watch"] {
  border-color: rgba(128, 83, 0, 0.24);
  background: #fffaf0;
}

.chemrytiq-page .chemrytiq-denovo-score[data-tone="risk"] {
  border-color: rgba(162, 45, 45, 0.24);
  background: #fff6f6;
}

.chemrytiq-page .chemrytiq-denovo-rules-score {
  display: grid;
  gap: 0.28rem;
  min-width: 0;
}

.chemrytiq-page .chemrytiq-denovo-rule-detail {
  min-width: 0;
}

.chemrytiq-page .chemrytiq-denovo-rule-detail summary {
  cursor: pointer;
  color: #526176;
  font-size: 0.68rem;
  font-weight: 850;
  line-height: 1.2;
  list-style-position: inside;
}

.chemrytiq-page .chemrytiq-denovo-rule-detail ul {
  display: grid;
  gap: 0.28rem;
  list-style: none;
  margin: 0.34rem 0 0;
  padding: 0;
}

.chemrytiq-page .chemrytiq-denovo-rule-detail li {
  border: 1px solid rgba(80, 102, 142, 0.16);
  border-left-width: 3px;
  border-radius: 6px;
  background: #ffffff;
  display: grid;
  gap: 0.1rem;
  padding: 0.34rem 0.4rem;
}

.chemrytiq-page .chemrytiq-denovo-rule-detail li[data-tone="good"] {
  border-left-color: #238653;
}

.chemrytiq-page .chemrytiq-denovo-rule-detail li[data-tone="watch"] {
  border-left-color: #9a6500;
}

.chemrytiq-page .chemrytiq-denovo-rule-detail li[data-tone="risk"] {
  border-left-color: #a22d2d;
}

.chemrytiq-page .chemrytiq-denovo-rule-detail li b {
  color: #172033;
  font-size: 0.68rem;
  line-height: 1.1;
  text-transform: uppercase;
}

.chemrytiq-page .chemrytiq-denovo-rule-detail li span {
  color: #172033;
  font-size: 0.74rem;
  font-weight: 800;
  line-height: 1.2;
}

.chemrytiq-page .chemrytiq-denovo-rule-detail li small {
  color: #69778c;
  font-size: 0.68rem;
  font-weight: 700;
  line-height: 1.25;
  margin: 0;
  overflow-wrap: anywhere;
  text-transform: none;
}

.chemrytiq-page .chemrytiq-denovo-score-delta {
  display: grid;
  gap: 0.36rem;
  min-width: 8.4rem;
}

.chemrytiq-page .chemrytiq-denovo-score-delta span {
  border: 1px solid rgba(80, 102, 142, 0.16);
  border-left-width: 3px;
  border-radius: 6px;
  background: #f9fbfd;
  display: grid;
  gap: 0.12rem;
  padding: 0.42rem 0.48rem;
}

.chemrytiq-page .chemrytiq-denovo-score-delta span[data-tone="good"] {
  border-left-color: #238653;
  background: #f4fbf6;
}

.chemrytiq-page .chemrytiq-denovo-score-delta span[data-tone="risk"] {
  border-left-color: #a22d2d;
  background: #fff6f6;
}

.chemrytiq-page .chemrytiq-denovo-score-delta span[data-tone="neutral"] {
  border-left-color: #69778c;
}

.chemrytiq-page .chemrytiq-denovo-score-delta b {
  color: #172033;
  font-size: 0.74rem;
  line-height: 1.1;
}

.chemrytiq-page .chemrytiq-denovo-score-delta small {
  color: #172033;
  font-size: 0.78rem;
  font-weight: 850;
  line-height: 1.15;
  margin: 0;
}

.chemrytiq-page .chemrytiq-denovo-score-delta em {
  color: #69778c;
  font-size: 0.68rem;
  font-style: normal;
  font-weight: 800;
  line-height: 1.2;
  text-transform: uppercase;
}

.chemrytiq-page .chemrytiq-denovo-pareto-badge {
  border: 1px solid rgba(25, 118, 210, 0.22);
  border-radius: 6px;
  background: #eef6ff;
  display: grid;
  gap: 0.1rem;
  margin-top: 0.35rem;
  padding: 0.38rem 0.45rem;
}

.chemrytiq-page .chemrytiq-denovo-pareto-badge b {
  color: #174d7d;
  font-size: 0.74rem;
  line-height: 1.1;
}

.chemrytiq-page .chemrytiq-denovo-pareto-badge small {
  color: #526176;
  font-size: 0.68rem;
  font-weight: 850;
  line-height: 1.2;
  margin: 0;
  text-transform: uppercase;
}

.chemrytiq-page .chemrytiq-denovo-pareto-detail {
  display: grid;
  grid-template-columns: repeat(2, minmax(0, 1fr));
  gap: 0.45rem;
  margin-top: 0.45rem;
}

.chemrytiq-page .chemrytiq-denovo-pareto-detail div {
  border: 1px solid rgba(80, 102, 142, 0.14);
  border-radius: 8px;
  background: #f9fbfd;
  display: grid;
  gap: 0.14rem;
  padding: 0.52rem 0.58rem;
}

.chemrytiq-page .chemrytiq-denovo-pareto-detail span {
  color: #69778c;
  font-size: 0.68rem;
  font-weight: 900;
  line-height: 1.2;
  text-transform: uppercase;
}

.chemrytiq-page .chemrytiq-denovo-pareto-detail strong {
  color: #172033;
  font-size: 1rem;
  line-height: 1.1;
}

.chemrytiq-page .chemrytiq-denovo-pareto-detail small {
  color: #526176;
  font-size: 0.68rem;
  font-weight: 700;
  line-height: 1.25;
  margin: 0;
}

.chemrytiq-page .chemrytiq-denovo-synthesis-card {
  border: 1px solid rgba(80, 102, 142, 0.16);
  border-radius: 8px;
  background: #ffffff;
  display: grid;
  gap: 0.55rem;
  padding: 0.72rem;
}

.chemrytiq-page .chemrytiq-denovo-synthesis-card > div:first-child {
  display: grid;
  gap: 0.16rem;
}

.chemrytiq-page .chemrytiq-denovo-synthesis-card span {
  color: #69778c;
  font-size: 0.68rem;
  font-weight: 900;
  line-height: 1.2;
  text-transform: uppercase;
}

.chemrytiq-page .chemrytiq-denovo-synthesis-card strong {
  color: #172033;
  font-size: 0.95rem;
  line-height: 1.2;
}

.chemrytiq-page .chemrytiq-denovo-synthesis-card small,
.chemrytiq-page .chemrytiq-denovo-synthesis-card p {
  color: #526176;
  font-size: 0.76rem;
  font-weight: 700;
  line-height: 1.35;
  margin: 0;
}

.chemrytiq-page .chemrytiq-denovo-synthesis-actions {
  display: flex;
  flex-wrap: wrap;
  gap: 0.45rem;
}

.chemrytiq-page .chemrytiq-denovo-synthesis-actions button {
  border: 1px solid rgba(25, 118, 210, 0.28);
  border-radius: 999px;
  background: #eef6ff;
  color: #174d7d;
  cursor: pointer;
  font-size: 0.76rem;
  font-weight: 900;
  padding: 0.45rem 0.7rem;
}

.chemrytiq-page .chemrytiq-denovo-rx-check {
  border: 1px dashed rgba(80, 102, 142, 0.22);
  border-radius: 8px;
  background: #f9fbfd;
  display: grid;
  gap: 0.38rem;
  padding: 0.55rem;
}

.chemrytiq-page .chemrytiq-denovo-rx-check ul {
  display: grid;
  gap: 0.28rem;
  list-style: none;
  margin: 0;
  padding: 0;
}

.chemrytiq-page .chemrytiq-denovo-rx-check li {
  border: 1px solid rgba(80, 102, 142, 0.12);
  border-radius: 6px;
  background: #ffffff;
  display: grid;
  gap: 0.08rem;
  padding: 0.38rem 0.45rem;
}

.chemrytiq-page .chemrytiq-denovo-rx-check b {
  color: #172033;
  font-size: 0.78rem;
  line-height: 1.2;
}

.chemrytiq-page .chemrytiq-denovo-overlay-card {
  border: 1px solid rgba(80, 102, 142, 0.16);
  border-radius: 8px;
  background: #ffffff;
  display: grid;
  gap: 0.6rem;
  padding: 0.72rem;
}

.chemrytiq-page .chemrytiq-denovo-overlay-metrics {
  display: grid;
  grid-template-columns: repeat(3, minmax(0, 1fr));
  gap: 0.45rem;
}

.chemrytiq-page .chemrytiq-denovo-overlay-metrics div {
  border: 1px solid rgba(80, 102, 142, 0.14);
  border-left-width: 3px;
  border-radius: 8px;
  background: #f9fbfd;
  display: grid;
  gap: 0.1rem;
  padding: 0.48rem 0.52rem;
}

.chemrytiq-page .chemrytiq-denovo-overlay-metrics div[data-tone="good"] {
  border-left-color: #238653;
}

.chemrytiq-page .chemrytiq-denovo-overlay-metrics div[data-tone="watch"] {
  border-left-color: #9a6500;
}

.chemrytiq-page .chemrytiq-denovo-overlay-metrics div[data-tone="risk"] {
  border-left-color: #a22d2d;
}

.chemrytiq-page .chemrytiq-denovo-overlay-card span,
.chemrytiq-page .chemrytiq-denovo-overlay-metrics span {
  color: #69778c;
  font-size: 0.66rem;
  font-weight: 900;
  line-height: 1.2;
  text-transform: uppercase;
}

.chemrytiq-page .chemrytiq-denovo-overlay-metrics strong {
  color: #172033;
  font-size: 1rem;
  line-height: 1.1;
}

.chemrytiq-page .chemrytiq-denovo-overlay-card small,
.chemrytiq-page .chemrytiq-denovo-overlay-card p {
  color: #526176;
  font-size: 0.74rem;
  font-weight: 700;
  line-height: 1.35;
  margin: 0;
}

.chemrytiq-page .chemrytiq-denovo-overlay-card button {
  justify-self: start;
  border: 1px solid rgba(25, 118, 210, 0.28);
  border-radius: 999px;
  background: #eef6ff;
  color: #174d7d;
  cursor: pointer;
  font-size: 0.76rem;
  font-weight: 900;
  padding: 0.45rem 0.7rem;
}

.chemrytiq-page .chemrytiq-denovo-overlay-explain {
  border: 1px dashed rgba(80, 102, 142, 0.22);
  border-radius: 8px;
  background: #f9fbfd;
  padding: 0.55rem 0.65rem;
}

.chemrytiq-page .chemrytiq-denovo-softspot-card {
  border: 1px solid rgba(80, 102, 142, 0.16);
  border-radius: 8px;
  background: #ffffff;
  display: grid;
  gap: 0.58rem;
  padding: 0.72rem;
}

.chemrytiq-page .chemrytiq-denovo-softspot-map {
  min-height: 14rem;
  border: 1px solid rgba(80, 102, 142, 0.14);
  border-radius: 8px;
  background: #fbfdff;
  display: grid;
  place-items: center;
  padding: 0.45rem;
}

.chemrytiq-page .chemrytiq-denovo-softspot-map svg {
  width: 100%;
  max-width: 28rem;
  height: auto;
}

.chemrytiq-page .chemrytiq-denovo-softspot-map span,
.chemrytiq-page .chemrytiq-denovo-softspot-map em {
  color: #526176;
  font-size: 0.74rem;
  font-style: normal;
  font-weight: 750;
  line-height: 1.35;
  text-align: center;
}

.chemrytiq-page .chemrytiq-denovo-softspot-map em {
  display: block;
  margin-top: 0.35rem;
}

.chemrytiq-page .chemrytiq-denovo-softspot-legend {
  display: flex;
  flex-wrap: wrap;
  gap: 0.5rem;
}

.chemrytiq-page .chemrytiq-denovo-softspot-legend span {
  color: #526176;
  display: inline-flex;
  align-items: center;
  gap: 0.3rem;
  font-size: 0.72rem;
  font-weight: 850;
  line-height: 1.2;
}

.chemrytiq-page .chemrytiq-denovo-softspot-legend i {
  width: 0.72rem;
  height: 0.72rem;
  border-radius: 999px;
  display: inline-block;
  box-shadow: 0 0 0 0.18rem rgba(245, 158, 11, 0.18);
}

.chemrytiq-page .chemrytiq-denovo-softspot-legend i.is-oxidative {
  background: #f59e0b;
}

.chemrytiq-page .chemrytiq-denovo-softspot-legend i.is-hydrolytic {
  background: #dc2626;
  box-shadow: 0 0 0 0.18rem rgba(220, 38, 38, 0.16);
}

.chemrytiq-page .chemrytiq-denovo-softspot-list {
  display: grid;
  gap: 0.4rem;
}

.chemrytiq-page .chemrytiq-denovo-softspot-list div {
  border: 1px solid rgba(80, 102, 142, 0.14);
  border-left: 3px solid #f59e0b;
  border-radius: 8px;
  background: #fffaf0;
  display: grid;
  gap: 0.14rem;
  padding: 0.48rem 0.55rem;
}

.chemrytiq-page .chemrytiq-denovo-softspot-list b {
  color: #172033;
  font-size: 0.82rem;
  line-height: 1.2;
}

.chemrytiq-page .chemrytiq-denovo-softspot-list span,
.chemrytiq-page .chemrytiq-denovo-softspot-list small {
  color: #526176;
  font-size: 0.72rem;
  font-weight: 750;
  line-height: 1.3;
}

.chemrytiq-page .chemrytiq-denovo-softspot-list small {
  color: #3f4d5f;
}

.chemrytiq-page .chemrytiq-denovo-filter {
  display: grid;
  width: 100%;
  box-sizing: border-box;
  gap: 0.15rem;
  border: 1px solid rgba(80, 102, 142, 0.16);
  border-radius: var(--chemrytiq-radius-sm, 0.75rem);
  background: #f9fbfd;
  padding: 0.5rem 0.6rem;
}

.chemrytiq-page .chemrytiq-denovo-filter b {
  color: #172033;
  font-size: 0.86rem;
  line-height: 1.1;
}

.chemrytiq-page .chemrytiq-denovo-filter small {
  color: #69778c;
  font-size: 0.7rem;
  font-weight: 800;
  line-height: 1.25;
  margin: 0;
  overflow-wrap: anywhere;
  text-transform: uppercase;
}

.chemrytiq-page .chemrytiq-denovo-filter[data-tone="good"] {
  border-color: rgba(17, 100, 61, 0.24);
  background: #f4fbf6;
}

.chemrytiq-page .chemrytiq-denovo-filter[data-tone="watch"] {
  border-color: rgba(128, 83, 0, 0.24);
  background: #fffaf0;
}

.chemrytiq-page .chemrytiq-denovo-filter[data-tone="risk"] {
  border-color: rgba(162, 45, 45, 0.24);
  background: #fff6f6;
}

.chemrytiq-page .chemrytiq-denovo-alert-summary {
  display: grid;
  gap: 0.36rem;
  margin-top: 0.45rem;
}

.chemrytiq-page .chemrytiq-denovo-alert-reasons {
  display: grid;
  gap: 0.2rem;
}

.chemrytiq-page .chemrytiq-denovo-alert-reasons span {
  color: #172033;
  font-size: 0.78rem;
  font-weight: 750;
  line-height: 1.3;
}

.chemrytiq-page .chemrytiq-denovo-alert-group {
  border: 1px solid rgba(105, 119, 140, 0.22);
  border-radius: 6px;
  display: grid;
  gap: 0.25rem;
  padding: 0.36rem 0.42rem;
}

.chemrytiq-page .chemrytiq-denovo-alert-group[data-tone="risk"] {
  border-color: rgba(162, 45, 45, 0.25);
  background: #fff7f7;
}

.chemrytiq-page .chemrytiq-denovo-alert-group[data-tone="watch"] {
  border-color: rgba(128, 83, 0, 0.22);
  background: #fffaf0;
}

.chemrytiq-page .chemrytiq-denovo-alert-group[data-tone="inherited"] {
  background: #f7f9fc;
}

.chemrytiq-page .chemrytiq-denovo-alert-group[data-tone="resolved"] {
  border-color: rgba(31, 133, 82, 0.26);
  background: #f2fbf6;
}

.chemrytiq-page .chemrytiq-denovo-alert-group strong {
  color: #546176;
  font-size: 0.66rem;
  letter-spacing: 0.03em;
  line-height: 1.2;
  text-transform: uppercase;
}

.chemrytiq-page .chemrytiq-denovo-alert-group div {
  display: flex;
  flex-wrap: wrap;
  gap: 0.24rem;
}

.chemrytiq-page .chemrytiq-denovo-alert-group span {
  border: 1px solid rgba(105, 119, 140, 0.18);
  border-radius: 999px;
  color: #172033;
  font-size: 0.7rem;
  font-weight: 800;
  line-height: 1.2;
  padding: 0.18rem 0.34rem;
}

.chemrytiq-page .chemrytiq-denovo-alert-group span[data-alert-tone="risk"] {
  border-color: rgba(162, 45, 45, 0.28);
  color: #8b2525;
}

.chemrytiq-page .chemrytiq-denovo-alert-group span[data-alert-tone="resolved"] {
  border-color: rgba(31, 133, 82, 0.3);
  color: #17673d;
}

.chemrytiq-page .chemrytiq-denovo-alert-group span[data-alert-tone="empty"] {
  color: #69778c;
  font-weight: 700;
}

.chemrytiq-page .chemrytiq-denovo-alert-summary em {
  border-left: 3px solid #1976d2;
  background: #f8fbff;
  color: var(--chemrytiq-text-soft, #445d73);
  font-size: 0.76rem;
  line-height: 1.35;
  padding: 0.35rem 0.45rem;
  overflow-wrap: anywhere;
}

.chemrytiq-page .chemrytiq-denovo-alert-summary small {
  color: #69778c;
  font-size: 0.7rem;
  font-weight: 800;
  margin: 0;
  text-transform: uppercase;
}

.chemrytiq-page .chemrytiq-denovo-detail {
  margin-top: 0.9rem;
}

.chemrytiq-page .chemrytiq-denovo-detail-collapse {
  padding: 0;
}

.chemrytiq-page .chemrytiq-denovo-detail-collapse[open] {
  padding-bottom: 0.85rem;
}

.chemrytiq-page .chemrytiq-denovo-detail-collapse .chemrytiq-denovo-detail-head,
.chemrytiq-page .chemrytiq-denovo-detail-collapse .chemrytiq-denovo-detail-grid {
  margin-left: 0.85rem;
  margin-right: 0.85rem;
}

.chemrytiq-page .chemrytiq-denovo-detail-collapse .chemrytiq-denovo-detail-head {
  margin-top: 0.85rem;
}

.chemrytiq-page .chemrytiq-denovo-detail-head {
  display: block;
}

.chemrytiq-page .chemrytiq-denovo-detail-head span {
  display: block;
  color: #69778c;
  font-size: 0.7rem;
  font-weight: 900;
  text-transform: uppercase;
}

.chemrytiq-page .chemrytiq-denovo-detail-head strong {
  display: block;
  color: #172033;
  font-size: 0.98rem;
}

.chemrytiq-page .chemrytiq-denovo-detail-title-row {
  display: flex;
  align-items: center;
  flex-wrap: wrap;
  gap: 0.55rem;
  margin-top: 0.15rem;
}

.chemrytiq-page .chemrytiq-denovo-detail-head button {
  min-height: 2rem;
  border: 1px solid var(--chemrytiq-border-strong, #c5d4e5);
  border-radius: 999px;
  background: #ffffff;
  color: #1565c0;
  cursor: pointer;
  font-size: 0.78rem;
  font-weight: 800;
  padding: 0 0.7rem;
}

.chemrytiq-page .chemrytiq-denovo-detail-grid {
  display: grid;
  grid-template-columns: minmax(16rem, 0.9fr) minmax(20rem, 1.1fr);
  gap: 0.85rem;
}

.chemrytiq-page .chemrytiq-denovo-detail-grid section {
  border: 1px solid rgba(80, 102, 142, 0.14);
  border-radius: var(--chemrytiq-radius-sm, 0.75rem);
  background: #f9fbfd;
  padding: 0.75rem;
}

.chemrytiq-page .chemrytiq-denovo-detail-grid h4 {
  margin: 0 0 0.55rem;
  color: #172033;
  font-size: 0.92rem;
}

.chemrytiq-page .chemrytiq-denovo-breakdown {
  display: grid;
  grid-template-columns: repeat(2, minmax(0, 1fr));
  gap: 0.45rem;
}

.chemrytiq-page .chemrytiq-denovo-breakdown div {
  border: 1px solid rgba(80, 102, 142, 0.14);
  border-radius: 0.65rem;
  background: #ffffff;
  padding: 0.5rem;
}

.chemrytiq-page .chemrytiq-denovo-breakdown span,
.chemrytiq-page .chemrytiq-denovo-breakdown small {
  display: block;
  color: #69778c;
  font-size: 0.7rem;
  font-weight: 800;
}

.chemrytiq-page .chemrytiq-denovo-breakdown strong {
  display: block;
  color: #172033;
  font-size: 1rem;
  margin: 0.15rem 0;
}

.chemrytiq-page .chemrytiq-denovo-detail-grid p {
  margin: 0.55rem 0 0;
  color: var(--chemrytiq-text-soft, #445d73);
  font-size: 0.8rem;
}

.chemrytiq-page .chemrytiq-denovo-comparison {
  display: grid;
  gap: 0.45rem;
}

.chemrytiq-page .chemrytiq-denovo-compare-row {
  display: grid;
  grid-template-columns: 4.4rem minmax(5rem, 0.7fr) minmax(8rem, 1.2fr) minmax(5rem, 0.7fr);
  align-items: center;
  gap: 0.55rem;
  border: 1px solid rgba(80, 102, 142, 0.14);
  border-radius: 0.65rem;
  background: #ffffff;
  padding: 0.55rem;
}

.chemrytiq-page .chemrytiq-denovo-compare-label {
  color: #69778c;
  font-size: 0.72rem;
  font-weight: 900;
  text-transform: uppercase;
}

.chemrytiq-page .chemrytiq-denovo-compare-value {
  display: grid;
  gap: 0.18rem;
  min-width: 0;
}

.chemrytiq-page .chemrytiq-denovo-compare-value.is-parent {
  border-radius: 0.5rem;
  background: #f5f9fd;
  padding: 0.35rem;
}

.chemrytiq-page .chemrytiq-denovo-compare-value span {
  color: #69778c;
  font-size: 0.66rem;
  font-weight: 900;
  text-transform: uppercase;
}

.chemrytiq-page .chemrytiq-denovo-compare-value strong {
  color: #10263d;
  font-size: 0.9rem;
  overflow-wrap: anywhere;
}

.chemrytiq-page .chemrytiq-denovo-compare-change {
  display: grid;
  gap: 0.45rem;
  min-width: 0;
}

.chemrytiq-page .chemrytiq-denovo-compare-chip {
  justify-self: center;
  min-width: 4.5rem;
  border-radius: 999px;
  background: #edf5ff;
  color: #165a9f;
  font-weight: 900;
  padding: 0.36rem 0.62rem;
  text-align: center;
}

.chemrytiq-page .chemrytiq-denovo-compare-change.is-up .chemrytiq-denovo-compare-chip {
  background: #e9fbf2;
  color: #047857;
}

.chemrytiq-page .chemrytiq-denovo-compare-change.is-down .chemrytiq-denovo-compare-chip {
  background: #eef5ff;
  color: #1d5fa7;
}

.chemrytiq-page .chemrytiq-denovo-compare-change.is-same .chemrytiq-denovo-compare-chip {
  background: #f1f5f9;
  color: #52677d;
}

.chemrytiq-page .chemrytiq-denovo-compare-track {
  position: relative;
  height: 0.24rem;
  border-radius: 999px;
  background: #e5ebf2;
  overflow: hidden;
}

.chemrytiq-page .chemrytiq-denovo-compare-track span {
  position: absolute;
  inset: 0 auto 0 0;
  min-width: 0.18rem;
  border-radius: inherit;
  background: #8b5cf6;
}

.chemrytiq-page .chemrytiq-denovo-compare-change.is-up .chemrytiq-denovo-compare-track span {
  background: #3b82f6;
}

.chemrytiq-page .chemrytiq-denovo-compare-change.is-same .chemrytiq-denovo-compare-track span {
  background: #94a3b8;
}

@media (max-width: 980px) {
  .chemrytiq-page .chemrytiq-denovo-header,
  .chemrytiq-page .chemrytiq-denovo-card-head {
    flex-direction: column;
  }

  .chemrytiq-page .chemrytiq-denovo-grid {
    grid-template-columns: 1fr;
  }

  .chemrytiq-page .chemrytiq-denovo-property-grid {
    grid-template-columns: repeat(2, minmax(0, 1fr));
  }

  .chemrytiq-page .chemrytiq-denovo-ranking,
  .chemrytiq-page .chemrytiq-denovo-sar-body,
  .chemrytiq-page .chemrytiq-denovo-detail-grid {
    grid-template-columns: 1fr;
  }

  .chemrytiq-page .chemrytiq-denovo-compare-row {
    grid-template-columns: 1fr;
  }
}

@media (min-width: 981px) and (max-width: 1320px) {
  .chemrytiq-page .chemrytiq-denovo-property-grid {
    grid-template-columns: repeat(5, minmax(0, 1fr));
  }
}